Principal Scientist in Oxfordshire

CK Group is looking for an Principal Scientist in Oxfordshire

Job description

CK Group are recruiting for an experienced and dynamic Scientist, at either Senior/ Principal level, to join an early-stage biotechnology start-up, based in Oxford, on a permanent basis.



The Company:


Our client is an early-stage biotechnology start up, combining artificial intelligence (AI), and advanced high-throughput TCR screening techniques to revolutionise the treatment of solid cancers.



Location: Oxford



The Role:


To lead the in vivo and in vitro validation of T-cell engagers, and help drive forward the development of TCR engineering and processes.



Responsibilities:

  • To perform high-throughput TCR display methods by purifying recombinant TCRs.
  • Carry out protein characterisation (expression, purification and biophysical analysis).
  • Design and characterise TCRs for disease targets.
  • Oversee lab protocols and technical documents.
  • To be hands-on in the lab and manage tissue culture preparations.
  • Skills in data analysis (using software R) for Next Gen Sequencing analysis - desirable.



Your Background:

  • PhD qualified (biochemistry, immunology, cell biology) plus strong laboratory experience (academia and industry).
  • Experience in in vivo and in vitro validation of T-cell engagers (TCEs).
  • Experience in Investigational New Drug (IND-enabling/ approval) - ESSENTIAL.
  • Expertise in cell and immunological assays (flow cytometry, ELISA) with knowledge around cloning and PCR.
  • Strong background in protein characterisation and biophysical characterisation.



Benefits:

Competitive salary, option for home working (as per project demands), stock options




Apply:

It is essential that applicants hold entitlement to work in the UK. Please quote job reference 141 244 in all correspondence.


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Extra information

Status
Open
Education Level
Secondary School
Location
Oxfordshire
Type of Contract
Part-time jobs
Published at
09-07-2025
Full UK/EU driving license preferred
No
Car Preferred
No
Must be eligible to work in the EU
No
Cover Letter Required
No
Languages
English

Part-time jobs | Secondary School

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