Preclinical In-Vitro Toxicology Scientist

Job description

Preclinical In-Vitro Toxicology Scientist up to c£70k + Bonus + Benefits

Hampshire, Full Time ABJ6761

ONSITE- 5 days – PERM

An exciting opportunity has arisen for an experienced In-Vitro Regulatory Toxicology Scientist to join a leading scientific research and product development organisation focused on in-vitro and pre-clinical assessment. This is an excellent opportunity for an experienced scientist to take a technically influential role within a multidisciplinary environment, contributing to advanced pre-clinical testing capabilities across in-vitro science, product development and regulatory toxicology.

You will provide technical expertise and scientific direction across in-vitro Regulatory and Genetic Toxicology, supporting pre-clinical research, product development and regulatory programmes. The role will suit an experienced toxicologist with strong hands-on laboratory expertise who can work independently, lead technical activities and collaborate with internal teams and external partners.

Key Responsibilities

• Provide technical expertise in the development and application of in-vitro Regulatory Toxicology approaches.
• Lead and execute in-vitro studies, delivering robust, reliable and scientifically defensible data.
• Develop, optimise and apply Neutral Red, Ames and in-vitro micronucleus assays.
• Apply complex cell culture, exposure techniques and biological testing methodologies to investigate product safety and potential human health effects.
• Interpret experimental findings and bridge in-vitro data with analytical, human-use and clinical information where appropriate.
• Provide technical direction for new testing capabilities, methodologies and assessment strategies.
• Plan and deliver technical work programmes to agreed timescales, quality standards and objectives.
• Collaborate with multidisciplinary teams across Preclinical Science, Analytical Science, Toxicology, Clinical and Product Development.
• Build relationships with external technical partners, CROs, academic groups and specialist consultants.
• Support method transfer, validation and implementation of new technologies.
• Ensure data is generated and managed in line with appropriate quality and regulatory requirements within controlled, quality-assured laboratory environments.
• Contribute to continuous improvement of laboratory methods, processes and scientific capabilities.
• Prepare, author and peer-review scientific reports, technical documentation, regulatory materials, presentations and publications.
• Support external scientific collaborations, including method transfer and inter-laboratory validation.

Experience & Skills Required

• Degree, MSc or PhD in Biological Sciences, Toxicology, Pharmacology, Biomedical Sciences, Cell Biology, Molecular Biology or a related discipline.
• Significant practical experience in in-vitro Regulatory Toxicology, Genetic Toxicology or pre-clinical area.
• Hands-on experience with Neutral Red, Ames and/or in-vitro micronucleus testing.
• Strong experience in complex cell culture, exposure techniques, biological assays and data interpretation.
• Experience developing, optimising, transferring or validating in-vitro testing methodologies.
• Understanding of relevant regulatory toxicology guidelines, including OECD, ECVAM and ICCVAM.
• Experience within a controlled, quality-assured laboratory environment, ideally with GMP, GLP or GxP.
• Ability to assess complex biological datasets using appropriate data analysis, computational or bioinformatics.
• Experience contributing to regulatory submissions, scientific reports, technical documentation or external scientific communications.

Desirable

• Experience in disease modelling, molecular toxicology or adverse outcome pathway frameworks.
• Knowledge of bioinformatics, computational biology or advanced biological data analysis.
• Experience with high-content screening, high-throughput assays or innovative in-vitro platforms.
• Experience managing CROs, suppliers or scientific collaborations.

Benefits: Up to £70k + up to 30% bonus + 20% pension

To Apply: Please contact Alison Basson on 0203 909 3782 / 07814 547 440 or apply quoting ABJ6761 to alison.basson@hudsonshribman.co.uk

Extra information

Status

Open

Education Level

Secondary School

Location

Hampshire

Type of Contract

Full-time jobs

Published at

02-09-2026

Profession type

Health / Medical

Full UK/EU driving license preferred

No

Car Preferred

No

Must be eligible to work in the EU

No

Cover Letter Required

No

Languages

English